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MEDI.SOLA

Evidence

EVIDENCE BASED NUTRi-SOLUTION

We prove the care journey through clinical intervention trials with university hospital teams in Korea.
Our nutritional principles, unchanged — and the proving through clinical work continues.

years of clinical trials
8+
clinical trial meals
25,000+
research papers published
37
patents and utility models
9

Four representative trials

Key research results, proven in clinical trials

With university hospital teams in Korea, we are proving MEDI.SOLA's nutritional principles through clinical intervention trials.

Dyslipidemia

Nutrients, 2021

Effects of a Calorie-Restricted Mediterranean-Style Diet on Plasma Lipids in Hypercholesterolemic South Korean Patients

Severance Hospital, Family Medicine | Lee JW, Son DH, Kwon YJ, Lee HS, Kim HM

  • · Period: Apr 2020 – May 2021
  • · Site: Gangnam Severance Hospital
  • · Participants: Korean patients with hypercholesterolemia
  • · Intake: 4 weeks, 5 days a week / twice a day

In patients with hypercholesterolemia, BMI and lipid markers (total and LDL cholesterol) improved significantly (p<0.001)

Read the paper (opens in a new tab)

Breast cancer

Frontiers in Nutrition, 2022

Effects of Single Nucleotide Polymorphisms and Mediterranean Diet in Overweight or Obese Postmenopausal Women With Breast Cancer Receiving Adjuvant Hormone Therapy

Severance Hospital, Family Medicine and Breast Surgery | Cho AR, Hong KW, Kwon YJ, et al.

  • · Period: Sep 2019 – Sep 2020
  • · Site: Gangnam Severance Hospital
  • · Participants: postmenopausal breast cancer patients (stage 1–3)
  • · Intake: 8 weeks, 5 days a week / twice a day

In postmenopausal cancer patients, BMI and body fat fell significantly (p<0.001)

Read the paper (opens in a new tab)

Chronic kidney disease

Frontiers in Nutrition, 2024

Safety and impact of the Mediterranean diet in patients with chronic kidney disease: a pilot randomized crossover trial

Severance Hospital, Family Medicine and Nephrology | Lee JW, Kwon YJ, Lee JE, et al.

  • · Period: Oct 2021 – Aug 2022
  • · Site: Yongin Severance Hospital
  • · Participants: Korean patients with kidney disease (non-dialysis, stage 3–4)
  • · Intake: 4 weeks, 5 days a week / twice a day

In pre-dialysis CKD patients, total carbon dioxide (tCO₂), a marker of metabolic acidosis, improved significantly (p=0.043)

Read the paper (opens in a new tab)

Hypertriglyceridemia

Nutr Res Pract, 2026

Efficacy of a Customized Korean–Mediterranean Diet in Managing Hypertriglyceridemia: A Pilot Study

Severance Hospital, Family Medicine | Seo Y, Lee JW, Kwon YJ, Kim HM, et al.

  • · Period: Oct 2023 – Oct 2024
  • · Site: Yongin Severance Hospital
  • · Participants: Korean patients with hypertriglyceridemia
  • · Intake: 2 weeks, 7 days a week / twice a day

In patients with hypertriglyceridemia, LDL particle size and lipid markers (triglycerides and total cholesterol) improved significantly (p<0.001)

Read the paper (opens in a new tab)

The archive

Published research using MEDI.SOLA

37 papers

2026

2025

2024

2023

2022

2021

Intellectual property

Registered patents

MEDI.SOLA patents and utility models
TitleNumberFiledStatus
Packaging Material Including Fold Lines and Packaging Method Using the Same접이선을 포함하는 포장재 및 포장재를 이용한 포장 방법10-2024-0080401Jun 2024FiledPatent
Method for Providing a Mediterranean Diet to Patients with Chronic Diseases만성 질환 환자에게 지중해식 식단 제공 방법10-2024-0112037Aug 2024FiledPatent
Platform-Based Method and Apparatus for Managing Patient-Specific Nutritional Status플랫폼 기반의 환자 맞춤형 영양 상태 관리 방법 및 장치10-2024-0113844Aug 2024FiledPatent
Method for Manufacturing Reverse-Type Packaged Food and Cook-Chilled or Cook-Frozen Packaged Food Manufactured Thereby리버스 형태의 포장 식품 제조 방법 및 그에 따라 제조된 쿡-칠 또는 쿡-프로즌 포장 식품10-2024-0172599Nov 2024FiledPatent
Method for Providing Catering Services Using Reverse-Type Cook-Chilled or Cook-Frozen Packaged Food and Process Thereof리버스 형태의 쿡-칠 또는 쿡-프로즌 포장 식품을 이용한 케이터링 제공 방법 및 그 프로세스10-2024-0172600Nov 2024FiledPatent
High-Protein, Sugar-Free, Gluten-Free, and Butter-Free Confectionery Composition Containing Whey Protein and Method for Manufacturing the Same유청단백질을 함유한 고단백, 설탕-프리, 글루텐-프리, 버터-프리 과자류 조성물 및 이의 제조방법10-2778321-00-00Mar 2025RegisteredPatent
Customized Real-Time Behavior-Based Health Management System Adaptable to Any Prescription임의의 처방에도 적응 가능한 맞춤형 실시간 행동 기반 건강 관리 시스템10-2025-0025239Feb 2025FiledPatent
Mediterranean Diet for Improving or Maintaining Renal Function in Patients with Chronic Kidney Disease만성 신장 질환 환자의 신장 기능 개선 또는 유지를 위한 지중해식 식단10-2025-0114299Aug 2025FiledPatent
Sleeve with Folding Lines폴딩라인을 포함하는 슬리브20-2024-0001085Jun 2024FiledUtility model

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